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Cardioprotective effects of lysyl oxidase inhibition

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The collagen cross-linking enzyme, lysyl oxidase (LOX), is elevated in many cardiac diseases and is associated with fibrosis. A new article explains that inhibition of LOX activity provided significant cardioprotection in a rat model of chronic volume overload (VO) stress. Rats with 8 weeks of established VO-induced disease were treated with a LOX inhibitor for […]

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A new approach to sequence and assemble primate genomes

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An improved version of the gorilla genome assembly is offering new biological insights into its evolution, and to what makes humans different from this great ape primate. The new techniques used to sequence and assembly this gorilla genome hold promise for improving genetic research on human disease. The techniques create longer reads of DNA sequences […]