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A protein that pulls the brake on nerve growth

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During embryonic development, nerve cells form thin, long extensions, which they use to wire up a complex network, the brain. Scientists have now identified a protein that regulates the growth of these extensions by pulling a brake. In the long run, their findings could help to develop new approaches for the treatment of spinal cord […]

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Evading Heisenberg isn’t easy

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Researchers unravel novel dynamics in the interaction between light and mechanical motion with significant implications for quantum measurements designed to evade the influence of the detector in the notorious ‘back action limit’ problem.

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Disease-causing protein in cystic fibrosis has ancient roots in sea lamprey

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The oldest known ortholog of the ion channel that is defective in patients with cystic fibrosis arose approximately 450 million years ago in the sea lamprey, researchers report. Many differences between lamprey and jawed vertebrate orthologs of this protein, called the cystic fibrosis transmembrane conductance regulator, are vestiges of the evolutionary transition from a transporter […]

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Important gene variants found in certain African populations

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In the nearly 20 years since the Human Genome Project was completed, experts in genetic variants increasingly have raised concerns about the overemphasis on studying people of European descent when performing large population studies. A study aims to address some of this disparity by focusing on populations living in rural Uganda, thus revealing several new […]