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A new breakthrough in developing effective antimalarial drugs

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Parasites in the genus Plasmodium, which cause malaria, are transmitted to humans through bites from infected mosquitoes. The parasites manage to acclimatize to these two completely different hosts because the plasticity of their genome enables them to adapt as necessary. Scientists decided to investigate the epigenetic mechanisms behind this plasticity, in particular DNA methylation. They […]

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Possible dementia vaccine closer after mice studies

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A vaccine to ward off dementia may proceed to clinical trials after successful animal testing. The research is looking to develop effective immunotherapy via a dual vaccine to remove ‘brain plaque’ and tau protein aggregates linked to Alzheimer’s disease. It is showing success in begenic mice models, supports progression to human trials in years to […]

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Combining neurologic and blood pressure drugs reduces breast tumor development in mice

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Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy. Conversely, this treatment combination increased breast cancer development in the […]