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Potential target for cardiac fibrosis treatment

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A research team has identified a potential target for treating heart failure related to fibrosis. The study looked at an epigenetic ‘reader’ protein known as BRD4, showing that it serves a central role in regulating the activation of cardiac fibroblasts. They also found that chemical inhibitors of BRD4 potently block cardiac fibroblast activation.

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Elusive compounds of greenhouse gas isolated

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Nitrous oxide (N2O) is a potent atmospheric pollutant. Although naturally occurring, anthropogenic N2O emissions from intensive agricultural fertilization, industrial processes, and combustion of fossil fuels and biomass are a major cause for concern. Researchers have isolated elusive transition metal compounds of N2O that provide clues into how it could be used in sustainable chemical technologies.

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Fungicides as an underestimated hazard for freshwater organisms

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Large amounts of fungicides, used in agriculture, leak into nearby surface waters. The effects of it on aquatic organisms are poorly understood and not specifically addressed in the EU regulatory frameworks with respect to the protection of surface waters. Scientists have found that pollution by fungicides can have unforeseen but far-reaching consequences for the functioning […]